I would say 8GB is the practical limit for anyone, really. The extra expense does not justify the gain beyond 8. I personally run 4.
You can run CAD software with 2GB. 2 should be your minimum, and 8 should be your maximum. From what I gather, there is very little noteworthy improvement from 6GB DDR3 to 12GB, so 8 is technically overkill already.
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