So what hotkeys do you have?
 

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1-hp stone
2-sp stone
3-hp pot
4-sp pot
q-auto attack
e-aimed shot
r-fury shot
f-bone shot
shift-poison shot
x-multi shot
t-natures protection
`-hobby
(Middle mouse button)- item pick up

i use tab to auto target cuz my mouse is laggy in the game, i hav huge hands so these are pretty easy moves

i kinda adapted from the Gunz layout, i played that for 8 months before i came here

1 - Invincible
2 - Pick up item (I can never have pick up motion on another hotkey in any game. It always have to be 2 for some reason, I can't get used to another hotkey for it!).
3 - HEAL!
4 - Bash
5 - Protect
6 - Resist
7 - Revive.
8 - Cure.
9 - The skill where you heal someone over a period of time. What was it called again?
0 - Nothing
Shift+5 - Horsey.
Shift+6 - Scroll making.

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1. stun
2. Pickup
3. Special attack
4. attack speed debuff
5. Defense debuff
6. dexterity debuff
7. Taunt
8. Aoe taunt
9. Aoe stun/special attack
0. Attack buff

I don't bother for anything else really.

1-Auto Attack
2-Pick up item
3-heal
4-Bash
5-Protect
6-Buff that increases magical defense
7-HP Stones
8-SP stones
9-Potion production
0-Scroll production
- is HP potions
= is SP potions
Shift+5-Cure
Shift+6-Revive

Because I like to fit all my skills for training in one bar and the ones that I don't use so often on the shift bar. =) I've got dancing emotes on the shift ones as well but I just don't remember which one was on which.

Mine is:

1-Aim
2-Bone Shot
3-Fury Impact
4-Power Shot
5-Auto Attack
6-Multishot

--SP Pot
=-HP Pot

Shift1-Nature's Protection
Shift2-Item Pickup
Shift=-Stone Production

Cleric:
1 - Auto attack (Useful for tabbing enemies that are difficult to click)
2 - Item Pick-up
3 - Cure
4 - Blank
5 - Trip
6 - Bash
7 - HP Stone
8 - SP Stone
9 - Heal
0 - Rejuvenate
- - Invincible
= - Periodic HP recovery
Shift + 1 - Stone Production
Shift + 2 - Scroll Production
Shift + 3 - Revive
Shift + 4 - Illness Protection
Shift + 5 - Shield Block Buff
Shift + 6 - Protect (PHYSICAL DEF)
Shift + 7 - Protect (MAGIC DEF)
Shift + = - Trade

Archer:
1 - Auto Attack
2 - Item Pick-up
3 - Power shot
4 - Other shot (lol don't remember)
5 - Bone Shot
6 - Fury Shot
7 - HP Pot
8 - SP Pot

Long list eh? :P

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Haha yeah, but I have a series of emotes and things on my shift bar, so might as well chuck the horse and scroll making in there as well. =) Not that I use those much anyway.

Currently, my set up is:
1: Auto Attack.
2: Pick up item.
3: Magic Missle.
4: Ice Bolt.
5: Fire Bolt.
6: Lightning Bolt.
7: HP potion (Tier 1).
8: SP potion (Tier 1).
9 & 10: Stone production/random emoticons.